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Symbol
Name
ID 		Tnnt2
troponin T2, cardiac
MGI:104597
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Myocardial sarcomeric disarray
Left atrial enlargement
Right atrial enlargement
Ventricular septal hypertrophy
Left ventricular hypertrophy
Left ventricular noncompaction
Dilated cardiomyopathy
Hypertrophic cardiomyopathy
Restrictive cardiomyopathy
Interstitial cardiac fibrosis
Aortic aneurysm
Stroke
Abnormal left ventricular function
Reduced left ventricular ejection fraction
Increased left ventricular end-diastolic volume
Mitral regurgitation
Tricuspid regurgitation
Hypotension
Pulmonary venous hypertension
Prolonged QT interval
Abnormal ST segment
Left axis deviation
Sinus bradycardia
Sudden cardiac death
Supraventricular arrhythmia
Atrial fibrillation
Incomplete right bundle branch block
Right bundle branch block
Angina pectoris
Congestive heart failure
Syncope
Disease(s) Associated with TNNT2
dilated cardiomyopathy 1D
hypertrophic cardiomyopathy 2
restrictive cardiomyopathy
restrictive cardiomyopathy 3

Mouse Phenotypes
perivascular fibrosis
abnormal myocardial fiber morphology
decreased myocardial fiber number
decreased myocardial fiber size
myocardial fiber degeneration
myocardial fiber disarray
disorganized myocardium
abnormal heart development
absent atrioventricular cushions
failure of heart looping
abnormal heart morphology
abnormal heart atrium morphology
increased heart atrium size
dilated heart atrium
decreased heart weight
enlarged heart
cardiac hypertrophy
small heart
abnormal heart ventricle morphology
abnormal heart left ventricle morphology
decreased heart left ventricle weight
decreased heart left ventricle size
dilated heart left ventricle
pericardial effusion
cardiac interstitial fibrosis
dilated heart
dilated cardiomyopathy
abnormal cardiovascular system physiology
abnormal cardiac muscle contractility
decreased cardiac muscle contractility
decreased ventricle muscle contractility
increased cardiac muscle contractility
abnormal cardiac muscle relaxation
decreased cardiac muscle relaxation
abnormal heart echocardiography feature
decreased left ventricle developed pressure
decreased left ventricle systolic pressure
decreased heart rate
increased heart rate
ventricular tachycardia
absent heartbeat
abnormal heart electrocardiography waveform feature
prolonged HV interval
prolonged QRS complex duration
prolonged QT interval
abnormal myocardial fiber physiology
cardiomyopathy
congestive heart failure
heart inflammation
Availability Mouse Genotype
Tnnt2tm1Feah/Tnnt2tm1Feah
Tnnt2tm1Mmto/Tnnt2tm1Mmto
Tnnt2tm2Mmto/Tnnt2tm2Mmto
Tg(Myh6-Tnnt2*)1Feah/0
Tnnt2tm1Feah/Tnnt2+
Tnnt2tm2.1Feah/Tnnt2+
Tnnt2tm2Mmto/Tnnt2+
Tg(Myh6-Tnnt2)117Lnwd/0
Tg(Myh6-Tnnt2)191Lnwd/0
Tg(Myh6-Tnnt2*)1Feah/0
Tg(Myh6-Tnnt2*R92L)1Jcf/0
Tg(Myh6-Tnnt2*R92Q)1Lnwd/0
Tg(Myh6-Tnnt2*R92Q)2Lnwd/0
Tg(Myh6-Tnnt2*R92Q)3Lnwd/0
Tg(Myh6-Tnnt2*R92W)1Jcf/0
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory